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Secretion and dipeptidyl peptidase-4-mediated metabolism of incretin hormones after a mixed meal or glucose ingestion in obese compared to lean, nondiabetic men

2023;120:e2221653120

Curiously, fat-induced OEA synthesis is a fairly conserved pathway in metazoan, being present in fish and extremely slow-metabolism reptiles such as pythons (325, 326)

Ultima Gold scintillation solution was purchased from Perkin Elmer (Waltham, MA, United States)

We used a node splitting approach to evaluate the agreement between direct and indirect estimates in each closed loop evidence, and a design treatment interaction model to assess the entire network.41 When continuous variables were missing, we used standard deviations borrowed from other similar randomised controlled trials to calculate the missing standard deviations

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