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Building on this initial imaging success, the National Institutes of Health (NIH) awarded a major grant for an ongoing randomized, double-blind, placebo-controlled clinical trial (NCT04542161) exploring much higher dosages of up to 3,600 mg/day of NAC

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In contrast, the ibuprofen-only group showed significant associations across all models, while the combined paracetamol plus ibuprofen group was significant in Models A and C, but not in Model B

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