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People taking oral Wegovy (semaglutide) saw a 15% weight-loss average in clinical trials, while those taking Foundayo (orforglipron) lost approximately 12% to 14% of their baseline weight

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Clinical data further reinforce these mechanistic insights

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10.1093/jac/dku534 95 RahmanR.GoyalV.HaqueR.JamilK.FaizA.SamadR.et al (2017)