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Research stage: Primarily animal studiesvery limited human clinical trials

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Mechanistically, NNMT suppression increased adipose SAM and NAD, upregulated polyamine flux enzymes (ODC, SSAT), and altered histone methylation consistent with a shift toward oxidative metabolism [2]

All scientific data referenced on this page derives from preclinical (animal / in vitro) models unless explicitly stated

it fundamentally improves how the cell processes energy

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