In OSF rats induced by betel nut extract administration through the buccal mucosa, EGCG hydrogel significantly reduces the expression of TGF-1 and type I collagen, with significant improvements in SOD and 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) clearance rate 145
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If you experience severe nausea, vomiting, or gastrointestinal distress, alcohol should be avoided until symptoms resolve
Baseline B12 assessment should be considered, particularly if you are taking metformin, following a plant-based diet, have had previous bariatric surgery, or have malabsorption conditions