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Minimize freeze-thaw cycles, which progressively degrade peptide integrity

PEGylation for Stability Harris and Chess (2003) reviewed PEGylation technology for peptide stabilization, describing how PEG attachment reduces proteolytic degradation and renal clearance to extend biological half-life [3]

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IV therapy typically provides higher doses directly into the bloodstream for faster systemic effects, while intramuscular injections may offer more gradual absorption