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Metabolite landscaping revealed that sertraline/chloroquine combination treatment blocks NADH and ATP generation and restricts nucleotide synthesis, thereby inhibiting glioblastoma proliferation
The samples were kept at 4C for 1 h, centrifuged at 1,200 g for 20 min at 4C and the supernatant was separated
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Besides exercise and nutrition, the paper also highlights weight loss, caloric restriction, and metabolic flexibility as key strategies to reduce oxidative load and improve glutathione recycling
PubMed laboratory research record [PMID: 21109554] PubMed record related to this compound for laboratory literature review
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