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In tolerance experiments with high doses of LPS-induced sepsis, changes in histone H3K4me3, H3K27me2, and histone methyltransferase complexes (102, 151, 152) can downregulate the genes encoding inflammatory factors while upregulating the anti-inflammatory factor genes (153, 154)
Elesclomol induces cancer cell apoptosis through oxidative stress
however, these findings need further investigation to be confirmed [218,219,220]
The clinical data indicate that slower escalation schedules reduce the severity of nausea and vomiting
Oxidative Medicine and Cellular Longevity , 2017 , 12