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192 , 455467, doi: 10.1164/rccm.201412-2233OC (2015)

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Older adults are at risk of magnesium deficiency due to reduced intestinal absorption and increased urinary excretion

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As with other glutathione peroxidases, GPx1 has a conserved catalytic tetrad composed of Sec or Cys, Gln, Trp, and Asn, where the Sec is surrounded by four arginines (R 57, 103, 184, 185