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A lower ratio generally indicates a more oxidized glutathione pool, but no universal reference interval applies across species, tissues, cells, or biofluids

Ectopic expression of SARS-CoV-2 S and ORF-9B proteins alters metabolic profiles and impairs contractile function in cardiomyocytes

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Indeed the activation of prodrugs in GST overexpressing cells may lead to high concentrations of an active drug, as compared to normal cells with moderate enzyme levels

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