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Good technique minimizes this, but does not eliminate it

It should be noted that GSH ester tends to be enriched inside cells due to its hydrophobic nature and esterase-catalyzed hydrolysis of GSH ester to GSH

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In recent years there has been considerable interest in the therapeutic potential of l-carnitine and its acetylated derivative acetyl-l-carnitine (ALCAR) for neuroprotection in a number of disorders including hypoxia-ischemia, traumatic brain injury, Alzheimers disease and in conditions leading to central or peripheral nervous system injury