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Patients should follow their specific prescription instructions rather than general guidance

For many peptides promoted for anti-ageing and skin health, high-quality human evidence remains limited

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Patients who have plateaued on a previous medication are candidates for the next step up

Other factors that contributed to the coverage change

European registry data highlight that there are likely various genetic causes of IGF-I deficiency which remain poorly characterized, with a confirmed GHR deletion or mutation accounting for only 13% of children receiving rhIGF-1 enrolled in the EU Increlex Growth Forum Database registry [14]