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SMD = 0.49)
excessive use may cause imbalances or mild adverse reactions
Prebiotics alone reduced levels of blood urea nitrogen and serum creatinine
Degraded peptide may have lost its copper-binding capacity, creating a solution of free copper rather than beneficial GHK-CU complex
For some patients, returning to or optimising conventional therapies such as metformin (if not already at maximum tolerated dose), sulphonylureas, or basal insulin may be appropriate
The standard protocol starts at 2.5 mg for the first four weeks
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