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If side effects persist, consider down-titrating to a lower dose for a longer period to allow for better tolerance and gradual adaptation

Wound Repair and Regeneration, 11(1), 19-24

FDA scientific reviewers had advised against adding any of the peptides, citing a lack of robust clinical evidence and unanswered safety questions, but supporters argued that regulated compounding would provide a safer alternative to the growing grey market, where the substances are widely sold as research-grade products despite not being approved for human use

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doi: 10.1186/s12916-024-03609-3