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Redox remodeling allows and controls B-cell activation and differentiation

Residues Y239 (TM5), Y358 (TM7) and F443 (TM10) all positioned ideally to form strong cation-\(\pi\) interactions, with nearby residues Y211, F359, Y387 and Y447 positioned within reasonable distance to form weak cation-\(\pi\) interactions

10.1007/s13562-016-0385-3 121 PeetersN.GuidotA.VailleauF.VallsM

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The peptide appears to influence multiple inflammatory pathways, potentially reducing cytokine activity and immune-mediated damage in intestinal tissues