[Crossref] Kuzminski AM, Del Giacco EJ, Allen RH, Stabler SP, Lindenbaum J (1998) Effective treatment of cobalamin deficiency with oral cobalamin
This genetic metabolic block severely impairs the body's ability to produce cellular energy and clear out neurotoxins, directly contributing to the hallmark symptoms of ME/CFS, including profound post-exertional malaise (PEM) and unrefreshing sleep
In such cases, the emergency help is called upon and a doctor should be contacted as soon as possible
The second is dose and route translation : even where an effect is real in a mouse, the human-equivalent dose is not a simple body-weight scaling, and as the route section above stressed there is no human bioavailability figure to anchor an oral-versus-injected comparison
Without enough B12, the body can develop megaloblastic anemia
ENERGY BOOST : B12 (Methylcobalamin) is an essential nutrient that plays a critical role in energy production