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429 Subsequent studies found that FtMt overexpression reduced ROS and the contents of unstable iron in cytoplasm and mitochondria

| 2020 | Experimental Gerontology

J Inherit.Metab Dis 2010;33(5):555-561

We and others also observed that Rickettsia species encode a conserved GSH S-transferase GstA 10 , which is a homolog of a cell division protein FzlA that adopts a GST fold but does not bind GSH in vitro 58,59

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However, significant challenges remain, including the synthesis of stable tripeptides with good tissue penetration, insufficient understanding of their mechanisms of action, the scarcity of studies in larger animal models and human trials, and the lack of direct head-to-head comparisons with larger peptides [75, 95]