Dose escalation is occasionally used in longer protocols (8+ weeks) where initial high-dose loading aims to saturate tissue receptors, followed by lower maintenance doses to sustain gene expression changes
Records should specify the dosage administered (in 100 mg units), method of administration (e.g., subcutaneous injection via infusion pump or syringe-type cartridge), date of treatment, and lot number for regulatory traceability (Coding Health, 2024)
Despite this, compounded versions continue to circulate through some pharmacies, and the clinical field around its use continues to evolve
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Li D, Zhang Y, Xu L, et al
used for tendon ruptures