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Phase 3 trial results (REDEFINE program) showed CagriSema produced approximately 22-25% body weight reduction, putting it in direct competition with tirzepatide and retatrutide
Its reported side effects include headache, tachycardia, flushing, hypotension and urinary urgency
There was not any great interest at that time. Even the Veteran Affairs Department, for whom Eng worked, wouldnt use department resources to file a patent for exendin-4
PubMed laboratory research record [PMID: 36077374] PubMed record related to this compound for laboratory literature review
The trade-off for the low price is simplicity: no berberine, no probiotic, so cravings tied to glucose swings may linger
A study showing berberine increases GLP-1 by 20% becomes clinically proven to boost GLP-1 without contextualizing what that means
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