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Mice lacking a functional SELENOF were found to develop nuclear cataract (lens opacification) at a very early age suggesting that SELENOF may be critical to the quality control system of protein folding in the lens (33)
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"Preventing familial ALS: a clinical trial may be feasible but is an efficacy trial warranted?"
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In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Mirzaa GM, Amemiya A, editors
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