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Interest in these medications has recently accelerated, largely for their weight-loss effects, although access to and use of GLP-1 RA medications may be impacted by high cost, limited insurance coverage for patients without T2D and medication shortages

230,231 By modulating the activity of K-ATP channels, GLP-1 indirectly controls the calcium signaling in -cells, thereby influencing glucagon secretion

The preclinical data are interesting enough to warrant proper human investigation, but it is not sufficient to justify self-experimentation

doi: 10.1021/acsami.5c05089 33 YunJZhangYZhangHXiaoFWangYXuPet al

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