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Healthcare providers can prescribe both medications together when clinically indicated, but this combination necessitates enhanced glucose monitoring, particularly during niacin initiation or dose escalation
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In a randomized controlled trial of 72 patients with type 2 diabetes and reduced heart rate variability, oral supplementation with 800 mg/day of lipoic acid for four months resulted in significant improvement in two out of four measures of heart rate variability compared to placebo (81)
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