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Interestingly, a number of intracellular proteins that can be released and act as endogenous inflammatory signalling molecules (also known as damage-associated molecular patterns) can undergo glutathionylation, including high mobility group box 1 protein (HMGB-1) 14 , proteins of the S100 family 15 , galectin-1 16 , peroxiredoxin-2 (Prdx2) 17 and heat-shock protein 70 (HSP70) 18
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It enhances strength and endurance and also reduces the risk of injuries
To exclude false negatives, all investigated GSTs were confirmed to be solubly and functionally produced by SDSPAGE analysis and an activity test with the generic GST substrate CDNB ( 5 ) (Extended Data Fig
10.3233/JAD-148007 J
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