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It is a pathologic condition deserving particular attention due to its severity and diffusion especially in Western countries for its alarming impact on health and care costs [1,2,3]

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Involvement of endoplasmic reticulum stress, autophagy, and apoptosis in advanced glycation end products-induced glomerular mesangial cell injury

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2013;8(10):e76274

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But, its important to consider the risks too

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These blends simplify administration to a single injection but limit dosing flexibility

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No large randomised controlled trials

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