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Glucagon-like peptide-1 ( GLP-1 ) receptor agonists, such as semaglutide (Wegovy) or tirzepatide (Zepbound), reduce hunger and cravings, making it easier to maintain a calorie deficit during plateaus
For example, diarrhoea occurs in approximately 8-17% of patients taking Ozempic and up to 20-30% with Wegovy
The Blue Horizon Difference
Many patients hold a lower dose longer if appetite suppression is already effective or if side effects need more time to resolve
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