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This combination is not FDA-approved, and no clinical trials have evaluated its safety or efficacy

Nature 407 : 390395 Shen ZX, Chen GQ, Ni JH, Li XS, Xiong SM, Qiu QY, Zhu J, Tang W, Sun GL, Yang KQ, Chen Y, Zhou L, Fang ZW, Wang YT, Ma J, Zhang P, Zhang TD, Chen SJ, Chen Z and Wang ZY (1997) Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): II

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[11] For retinol, a systematic review identified it as the most clinically investigated retinoid derivative, though a separate systematic review specifically of OTC retinol products noted methodological limitations in much of the available evidence