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Step 7: Dont assume a denial is the final answer A denial is information, not a verdict

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Emphasize adequate hydration, monitor for signs of volume depletion, and check renal function at baseline, 4 weeks, 12 weeks, and any time side effects worsen

Other factors impacting bone health may include cellular changes, genetic damage due to complex age-related changes as well as nutritional deficiencies of calcium and vitamin D

A naturally occurring GIP receptor variant undergoes enhanced agonist-induced desensitization, which impairs GIP control of adipose insulin sensitivity