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The complete coding algorithms used for identifying patient characteristics, clinical diagnoses, medical procedures, pharmaceutical prescriptions, and laboratory parameters are detailed in Supplementary Table 1

Research indicates that this combination yields benefits such as improved deep sleep, reduced triglycerides, visceral adipose tissue, and carotid intima media thickness, enhanced cognition, and overall improved metabolic function

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The tonicity agent may be selected from the group consisting of mannitol, sorbitol or trehalose, or a combination thereof

In addition, ROS have been implicated in cyclic endometrial remodeling [22, 23], modulation of estrogen and progesterone responses [31, 32], and immune cell recruitment during the window of implantation [25, 33]