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ER and sarcoplasmic reticulum stress regulation complements these effects: HS pretreatment downregulates GRP78/CHOP/ATF6 expression induced by I/R, blocking pro-apoptotic ER stress signaling (Li et al., 2015)

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It increases the risk of corrosion. In their study, OWASA and UNC addressed the issue of corrosion with pilot scale testing to confirm the suitability of the reclaimed water for use in the cooling towers

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Sonntag K-C, Ryu W-I, Amirault KM, Healy RA, Siegel AJ, McPhie DL, et al