You have a BMI of 27 or higher plus a weight-related comorbidity approved by Cigna, including (but not limited to) hypertension, Type 2 diabetes, obstructive sleep apnea, and CV disease
Future iterations may be weekly oral tablets instead of daily dosing
These are mainly due to the structural and functional differences manifested among various species, which affect paracrine interactions within the islet
Spoiler: oral glutathione bioavailability is 10% or less in most formulations because peptide bonds are cleaved by gastric pepsin and intestinal peptidases before absorption
This pathway primarily influences insulin secretion and glucagon inhibition in pancreatic beta and alpha cells, respectively
This metabolic shift is separate from any direct drug effect on thyroid tissue and reflects your body's natural adjustment to a lower weight