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For example, glucose is the main substrate that photoreceptors utilize to create ATP in vivo 12 , but they can oxidize lipids, lactate, and use amino acids, fatty acids (such as palmitate) and other intermediate substrates to produce ATP, especially under glucose-deprived conditions 10,11,12

Potential for Muscle Maintenance : When paired with regular exercise, Semaglutide can support fat loss while maintaining lean muscle

Public written comments can be submitted to docket FDA-2025-N-6895 through July 22, 2026

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