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With a growing number of patients using these medications for diabetes or to meet certain optimization goals before undergoing hip and knee reconstructive surgery, our aim was to establish evidence-based guidelines on when to discontinue these to enhance patient safety and surgical success. The study, Optimal Timing for Cessation of GLP-1 Agonist Before Elective Total Hip and Knee Arthroplasty, obtained data from the TriNetX Research Network, a multi-institutional national aggregated database, to identify patients who underwent TKA or THA from January 1, 2018 to January 1, 2023

Lopresti, Adrian L et al

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The mTOR pathway The mTOR pathway is the major mechanisms for protein synthesis, and because this pathway was reported to be delayed in the elderly [38], protein analysis of mTOR and its downstream effectors p70-S6K and 4EB-P1 were conducted from muscle biopsy samples (Fig

To date, only one case of acrodermatitis enteropathica has been reported among patients using KDit emerged in an 11-year-old boy with drug-resistant epilepsy (253)