Influence of glucagon on GFR and on urea and electrolyte excretion: direct and indirect effects
While agonist peptides based on either scaffold are potent in rat obesity models 2,10,11,12,13 , only a transient weight loss effect is observed with sCT in mouse diet-induced obesity (DIO) models 14 , indicating that there may be distinctions in the mode of action of individual dual agonists
Sikiric et al., 2018) as well as counteracting harmful escape from the initial healing effect (i.e., angiogenesis)
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