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Through biochemical and structural analysis, here we show that anthocyanin-related glutathione transferases, currently implicated only in anthocyanin transport, catalyse an essential dehydration of the leucoanthocyanidin dioxygenase product, flavan-3,3,4-triol, to generate cyanidin
With adequate glutathione available for conjugation, the liver can efficiently bind to circulating histamine and other inflammatory cytokines, rendering them water-soluble for rapid excretion
[] Notably, certain microbiota-derived bile acids like 3-succinylated cholic acid may alleviate metabolic dysfunction-related steatohepatitis (MASH) by promoting Staphylococcus aureus growth
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Cruzat, V
Pui CH, Mullighan CG, Evans WE, Relling MV
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