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Patients living with obesity and PCOS often present significant visceral fat accumulation, resulting in elevated free fatty acid release that contributes to increased hepatic total cholesterol synthesis and dyslipidemia, manifesting as elevated triglyceride, total cholesterol, and LDL-C levels

Statements Author contributions All authors made substantial contributions to the work and approved the final version of the manuscript

It is not the active ingredient in any FDA-approved drug product, and there is no United States Pharmacopeia (USP) monograph for either AOD-9604 (free base) or AOD-9604 acetate

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However, this increase in myofibroblastic marker expression was not reflected at the protein level for either SMA (Fig