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Clinicians weigh BMI, waist circumference, co-morbidities, past weightloss attempts, lab results, and personal or family thyroidcancer history to ensure benefits exceed risks

This syndrome is characterized by clinical symptoms of sickness behavior such as leaden paralysis of the limbs, hypersomnia, and hyperphagia/weight gain, while mood reactivity is unimpaired, i.e., mood brightens in response to positive events (according to DSM-5 criteria for MDD with atypical features), while still suffering from lack of concentration and higher levels of exhaustibility as in melancholic MDD [99]

10.1007/s12011-020-02515-y 71 WangX.HanY.ChenF.WangM.XiaoY.WangH.et al (2022)

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