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By simultaneously activating incretin and glucagon pathways, it influences central satiety circuits and peripheral metabolic processes

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Retatrutide in MASLD and MASH: Why the Glucagon Arm Matters MASLD (metabolic dysfunction-associated steatotic liver disease, formerly NAFLD) affects an estimated 38% of adults globally according to a 2023 meta-analysis in the Journal of Hepatology

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Skaper SD (2012) The neurotrophin family of neurotrophic factors: An Overview