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However, many patients pay significantly less with insurance coverage

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While DCI is necessary for glycogen synthesis in the liver and muscles, an excess of DCI in the ovaries can hyper-stimulate theca cells, leading to an overproduction of testosterone and other androgens

While they have not yet been shown to reduce cardiovascular events directly, their use may help support uninterrupted guideline-directed medical therapy (GDMT) and allow clinicians to maintain or up-titrate RAASi and MRA therapy