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Some people on GLP-1 medications do experience more serious side effects like bowel obstruction, gallstone attacks, or gastroparesis (a condition where your stomach muscles dont move food in the way they should)

doi: 10.1016/j.immuni.2022.01.003 57 ThorssonVGibbsDLBrownSDWolfDBortoneDSOu YangTHet al

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In a retrospective study, this model was able to accurately predict whether the overdose would lead to fatal liver damage