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While 73% of Americans are either overweight or have obesity, there are open questions about the use of GLP-1s in people who are not overweight will these medications cause excess weight loss and, in particular, excess muscle loss

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But a question often arises in discussions about bodyweight exercises: Do pushups actually build muscle

Bimagrumab addresses a critical unmet need. Mark Pruzanski The advantage: While people on GLP-1 agonists tend to gain back any weight lost if they stop taking the meds, that might not be the case for bimagrumab 12 weeks after their last dose, the people in the 1,000-person phase 2 trial had yet to regain any weight

Despite its broad prospects, optimizing delivery systems (such as selecting AAV serotypes) to improve targeting and addressing safety issues in clinical translation remains necessary

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