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To overcome these challenges, strategies 5 such as pH optimization, use of stabilizing excipients (buffers, antioxidants, surfactants), lyophilisation, and controlled storage conditions are employed

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Five peaks with multiple mass shifts of 137 Da, expected the molecular mass of bound MQ, were found after incubation of Trx1 with MQ at a ratio of 1:11:5, indicating modification of all 5 thiols at this concentration

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