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It enhances glucosedependent insulin secretion and slows gastric emptying

Zhao, Y., Li, Y., Zhang, Y., Liu, F., Zhu, D., & Sun, Y

Emerging clinical evidence, including cardiovascular outcome studies such as the SELECT trial, suggests the therapies may reduce major cardiac events

Obesity has impacts on cardiovascular disease outcomes through increased risk of coronary artery disease, heart failure (more prominent with preserved ejection fraction), cardiac arrhythmias (most significantly atrial fibrillation), sudden death, and venous thromboembolism [7]

In severe cases of gout that do not respond to other treatments, surgery may be necessary to remove uric acid crystals from the affected joint

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