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Soucy F and Grgoire M: Efficacy of prednisone for severe refractory ulcerative interstitial cystitis
The Billon 2025 paper (PMID 41421047) is the citation that anchors the route question: SLU-PP-915 was developed because SLU-PP-332 "lacks oral bioavailability." If the parent compound does not absorb orally, oral capsules and tablets are unlikely to produce the systemic ERR agonism seen in mice
Out-of-pocket costs change often, and insurance reimbursements vary widely
It does not bind androgen, estrogen, progesterone, or glucocorticoid receptors, does not aromatize, and has no effect on the HPG or HPT axes
J Neuro-Ophthalmol 23(2):157163