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Notably, in these studies, the upregulation of GPx4 has been achieved by using exogenous agents (like NVP-AUY922, Bafilomycin A1, PD151746, GsMTx4, epigallocatechin-3-gallate, total flavonoids of Engelhardia roxburghiana leaves, Lycium barbarum polysaccharide-glycoprotein, perillaldehyde, melotonin, ferulic acid, and sphingosine-1-phosphate) which either inhibit the degradation of GPx4 or increase its transcription by activating the Nrf2 [67]

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Tomin, T., Schittmayer, M., & Birner-Gruenberger, R

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4, the modified GPx-DTNB assay exhibits a linear response to GPx activity within the concentration range of 21000 units per liter (U/L), with an excellent correlation coefficient ( r = 0.999)

Different skin types respond differently