The statistical analyses were performed using Prism9 GraphPad and generally included a ROUT outlier analysis
GLP-1RAs provide different mechanistic effects including anti-oxidative, anti-inflammatory, and anti-atherosclerotic properties [4, 9, 11, 14, 17]
Additionally, its short half-life in vivo limits its efficacy, as the drug is cleared within minutes of administration 16
Data from longer-term treatment will therefore be eagerly awaited to determine the extent of body weight loss and metabolic outcomes and whether this is comparable to the latest GLP-1 mono-agonist therapies
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