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If you lose weight through nutrition and exercise, through a GLP-1, or a surgical intervention, the brain and the body will try to resist that weight loss, Kumar says

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In April 2026, the FDA published a formal proposal in the Federal Register to remove semaglutide, tirzepatide, and liraglutide from the 503B outsourcing bulks list, with a public comment period open through June 2026

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Clinical Risks of Combining GLP-1 Medications with Cannabis The primary documented risks include unpredictable nausea and vomiting, delayed gastric emptying, impaired glucose monitoring, and potential hepatic stress