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133 Two alternative, Rag-independent ways of mTORC1 activation were also recently described

These findings suggest that antidepressants should be considered not merely as symptomatic mental health treatments, but as systemic immunomodulators that can stabilize the gut source of neuroinflammation, potentially reducing the frequency of IBD clinical flares (Di Petrillo et al., 2025)

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See SLU-PP-332 Side Effects for the documented adverse-event picture

After 4 weeks of the initial dosage, doctors may increase the dosage every 4 weeks until you reach the dose thats right for you