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The quantification was set to Robust LC (high precision) mode with normalization disabled, MBR enabled, protein inferences set to Genes and Heuristic protein inference turned off

A Phase 1a, blinded, placebo-controlled, randomized, single- and multiple-ascending-dose study was done to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of single and multiple doses of orforglipron

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It is transmitted by the bite of a deer tick