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This finding highlights PLC2 as a checkpoint molecule within MDSCs that can be targeted to alleviate immune suppression [158]

Therefore, the usage of dietary fibers entirely depends on CAZymes

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It also have anticarcinogenic effects since it inhibits cancer cells proliferation especially colon cancer through apoptosis and controls genes expression by inhibiting the histone deacetylase activity ( Faecalibacterium prausnitzii cannot be cultivated axenically in a medium without acetate ( Intestinal TJ proteins are involved in the regulation of barrier status which defines how the composition of the microbiota in the gut interacts with the immune cells

10.1126/science.289.5484.1567

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