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The FDA has approved the first oral glucagon-like peptide-1 (GLP-1) receptor agonist for weight loss and to reduce the risk of major adverse cardiovascular events (MACE)
Initially observed in people with type 2 diabetes using GLP-1 medications over long periods, the potential benefits of GLP-1 medicines are now being investigated in clinical trials for Alzheimers disease, arthritis, substance use disorders and other conditions
Scott EM, Bilous RW, Kautzky-Willer A (2018) Accuracy, user acceptability, and safety evaluation for the FreeStyle libre flash glucose monitoring system when used by pregnant women with diabetes
Exendin-4 (exenatide), a GLP-1 peptide encoded by lizard genes that is resistant to DPP-4-mediated catalytic degradation, received FDA approval in 2005 and became the first GLP-1RA available for public use
Common GLP-1 Medications Several GLP-1 receptor agonists are commonly prescribed
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